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Categories:
Proteins
|
Nephrology
cystatin C
(
structure
pictured)
is a human
protein
studied as a
biomarker
of decreased
kidney function
and
prognosis
in
cardiovascular diseases
?
Facts on topics related to Cystatin C
Protein
Europe's
most powerful
supercomputer
,
MareNostrum
, will be used in
human genome
research,
protein
research,
weather forecasting
and the design of new drugs?
proteins
are often broken down into smaller fragments by
in-gel digestion
before they are analysed by
mass spectrometry
?
cell adhesion
is a product of
protein
bonding?
coccolithovirus
, a giant double-stranded
DNA
virus
, has 472
protein
-coding
genes
, and is the largest known marine virus by
genome
?
cystatin C
(
structure
pictured)
is a human
protein
studied as a
biomarker
of decreased
kidney function
and
prognosis
in
cardiovascular diseases
?
DNA clamp
proteins
(pictured)
keep the
DNA polymerase
replicating enzyme bound to the template
DNA
strand, increasing the rate of
DNA synthesis
up to 1,000-fold?
Dr. Edward Smith
showed that
muscles
did not get their energy from
proteins
but from
fats
and
carbohydrates
?
Hans Freeman
introduced
protein crystallography
to
Australia
and determined the structure of
plastocyanin
, the first
protein
to be structurally characterised in the
southern hemisphere
?
Jane S. Richardson
developed the ubiquitous
ribbon diagram
method of representing
proteins
?
Jean-Claude Latombe
's
motion planning
algorithm
Probabilistic Roadmap Method
not only applies to robotic motion planning, but can also be used in
protein
trajectories
simulations
?
DNA
New York
abstract painter
Dennis Ashbaugh
is one of the first artists to employ
DNA
marking patterns in
paintings
?
Cetartiodactyla
is a
hypothesis
based on
DNA
that suggests
whales
and
hippos
are related?
coccolithovirus
, a giant double-stranded
DNA
virus
, has 472
protein
-coding
genes
, and is the largest known marine virus by
genome
?
DNA clamp
proteins
(pictured)
keep the
DNA polymerase
replicating enzyme bound to the template
DNA
strand, increasing the rate of
DNA synthesis
up to 1,000-fold?
genetic monitoring
of the
DNA
from feathers shed by the
Eastern Imperial Eagle
shows it is shorter lived than other long-lived raptors?
nucleic acid design
is used in
DNA nanotechnology
and
DNA computing
to create structures out of
DNA
, such as
nanomachines
, polyhedra
(example pictured)
, and
nanoscale origami
?
square root biased sampling
was originally developed as a way to sample long sequences of
DNA
?
a new
orchid
species,
Ornithidium donaldeedodii
, was "discovered" when a mislabeled plant at the
University of California Botanical Garden
had its
DNA
analyzed?
in a review of
David Jordan
's debut album,
Set the Mood
, it was suggested that the singer could have been
cloned
from the
DNA
of
Lenny Kravitz
,
Prince
and
Michael Jackson
?
more than 98% of the
human genome
is
noncoding DNA
, sometimes referred to as "junk"
DNA
?
Gene
mutations
in the
FLNB
gene
cause
boomerang dysplasia
, a lethal
congenital disorder
in which the limbs'
long bones
malform into the shape of a
boomerang
?
mutations
of the
ATN1
gene
result in
dentatorubral-pallidoluysian atrophy
, a
neurological disorder
with diverse problems as
dementia
,
ataxia
,
seizures
and
obstructive sleep apnea
?
microchromosomes
are very tiny
gene
-rich
chromosomes
which are a typical
genetic
component in
birds
, and some groups of
non-mammalian
animals?
spatiotemporal gene expression
refers to the patterns in which
genes
are expressed in different
tissues
as an
organism develops
?
a researcher at the
University of Minnesota College of Biological Sciences
discovered that the linear arrangement of
genes
on a
chromosome
corresponds to the development of body segments in
fruit flies
?
although the
extinct
Norfolk Island Boobook
was last sighted in 1996, its
genes
live on in the
hybrid
descendants of the last living female bird?
despite being in different
classes
,
Bradyrhizobium
and
Klebsiella pneumoniae
have similar
genes
for
fixing nitrogen
?
the
gene
that creates the crest of the
Bali Duck
also causes
physical defects
which can kill it before it
hatches
?
the
T4
rII
experimental system
enabled
biologist
Seymour Benzer
to map a
gene
down to the level of one or two
base pairs
before the invention of
DNA sequencing
?
Myocardial infarction
a 2009 study found that
Polycap
—a five-in-one
polypill
combining three
high blood pressure
medications, a cholesterol reducer and
aspirin
—could cut
heart attack
and
stroke
risk in half for many?
attorney
P. Cameron DeVore
died of an apparent
heart attack
, but jested in a self-written obituary that he had succumbed to "a surfeit of
pâté de foie gras
ice cream smothered in
huckleberries
"?
the
inbred
villagers of
Stoccareddo
in
Italy
are a medical phenomenon, with unusually low frequencies of
hypertension
,
strokes
and
heart attacks
despite a high-
cholesterol
diet
?
Obesity
Fay Boozman
, as the
state
health director under
Governor
Mike Huckabee
, managed the "Healthy
Arkansas
" initiative, including the fight against
obesity
?
MOMO syndrome
is a very rare
genetic disorder
characterised by
m
acrosomia
,
o
besity
,
m
acrocephaly
and
o
cular abnormalities
?
the
small bowel bacterial overgrowth syndrome
is a rare complication of
bariatric surgery
for
obesity
?
Amino acid
even one hundred years after its discovery, the role of the
amino acid
ergothioneine
(molecule pictured)
in the
human body
remains a mystery?
the
amino acid
glutamine
can be
broken down
to produce
glutamate
,
aspartate
,
carbon dioxide
,
pyruvate
,
lactate
,
alanine
and
citrate
?
the presence of
indoleic acid
in one's
urine
may indicate a
pathological accumulation
of the
amino acid
tryptophan
in the
blood
?
Enzyme
biochemists
Ralph F. Hirschmann
and
Robert Bruce Merrifield
both led teams that synthesized the
enzyme
ribonuclease
and while Merrifield won the
Nobel Prize in Chemistry
, Hirschmann did not?
Boneless Fish
is a
Japanese
frozen food
made from
fish
, which is
deboned
by hand and then glued to its original shape using a
food
-grade
enzyme
?
renalase
is an
enzyme
that breaks down
stress hormones
and decreases
blood pressure
?
measuring the levels of certain
enzymes
called
transaminases
can help to diagnose some
liver
diseases?
the
enzyme
neprilysin
(pictured)
degrades
amyloid beta
, a
peptide
whose abnormal aggregation is implicated as a cause of
Alzheimer's disease
?
the
venom
of the
Beaded Lizard
(pictured)
has been found to contain several
enzymes
useful in the manufacturing of drugs to treat
diabetes
?
the
Gaussian Network Model
has a wide range of applications from
enzymes
composed of a single
domain
, to large
macromolecular assemblies
, such as
ribosomes
and
viral capsids
?
the presence of the
metal
ion
in
metalloprotein
enzymes
allows them to perform functions, such as
catalyzing
redox
reactions, that other
polypeptide
enzymes cannot achieve?
the white bird's nest mushroom
Crucibulum laeve
(pictured)
produces a chemical that inhibits an
enzyme
implicated in the formation of
cataracts
in individuals with
diabetes mellitus
?
HIV
Botswana
international footballer
Donald Thobega
was involved in the Test For Life campaign, which encourages supporters to get tested for
HIV
and
AIDS
?
Czech
scientist
Antonín Holý
cooperated on the development of important
antiretroviral drugs
used in the treatment of
HIV
and
hepatitis B
?
Michael Jackson
's "
Gone Too Soon
" was dedicated to the memory of
Ryan White
, a teenager who died following a battle with
HIV
/
AIDS
?
NBC
network executive
Perry Lafferty
produced the 1985
television movie
An Early Frost
, one of the first dramatic films to deal with the subject of
HIV
/
AIDS
?
Gideon Byamugisha
was the first religious leader in Africa to publicly announce that he was
HIV
positive?
Jeannette Kagame
, the current
First Lady
of
Rwanda
, works to help victims of the
Rwandan Genocide
and
HIV
/
AIDS
?
Moscow Gay Pride
has been described as "
satanic
" and likely to increase the spread of
HIV
/
AIDS
by
Moscow Mayor
Yuri Luzhkov
(pictured)
?
Inventing the AIDS Virus
, written by
molecular biologist
Peter Duesberg
, argues that
AIDS
is not
infectious
and that
HIV
is an unrelated
passenger virus
?
according to
(RED)
, providing health-restoring
antiretroviral drugs
to
HIV positive
people in Africa, as described in the documentary
The Lazarus Effect
, costs
US$
0.40 per person per day?
the
anabolic steroid
Oxandrolone
was granted
orphan drug
status in treatment of
alcoholic hepatitis
,
Turner's syndrome
and
HIV wasting syndrome
?
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