• ADP-ribosylation, a posttranslational protein modification, is involved in the actions of several bacterial toxins in diseases such as cholera and whooping cough?

Facts on topics related to Posttranslational modification

Amino acid

• even one hundred years after its discovery, the role of the amino acid ergothioneine (molecule pictured) in the human body remains a mystery?
• the amino acid glutamine can be broken down to produce glutamate, aspartate, carbon dioxide, pyruvate, lactate, alanine and citrate?
• the presence of indoleic acid in one's urine may indicate a pathological accumulation of the amino acid tryptophan in the blood?

Proteolysis

• human amyloid precursor protein (pictured), when cleaved by specific types of proteases, generates the amyloid beta peptide that may be a cause of Alzheimer's disease?

ADP-ribosylation

• ADP-ribosylation, a posttranslational protein modification, is involved in the actions of several bacterial toxins in diseases such as cholera and whooping cough?